Selank
★ 72Selank (TP-7)
Anxiety relief without sedation
CognitiveAbout
A Russian nootropic peptide that reduces anxiety without sedation. Analog of tuftsin.
Mechanism
Modulates GABA and serotonin systems. Increases BDNF.
Dosage
beginner
- Amount
- 250-500 mcg
- Frequency
- 1-2x per day (nasal)
- Route
- Intranasal
- Duration
- 4-6 weeks
standard
- Amount
- 750-1500 mcg
- Frequency
- 2-3x per day (nasal) or 1x SubQ
- Route
- Intranasal or SubQ
- Duration
- 4-6 weeks
advanced
- Amount
- 2000-3000 mcg total daily
- Frequency
- Split into 2-3 doses
- Route
- Intranasal
- Duration
- 6 weeks on, then 2 weeks off
Morning or early afternoon. Avoid after 3 PM (may disrupt sleep).
4-6 weeks on, 1-2 weeks off.
Reconstitution & Storage
Most often used as a nasal spray. Each puff = 250-500 mcg.
Lyophilized: freezer. Reconstituted: 2-8°C, 14-21 days.
Benefits
- • Anxiety relief without sedation
- • Improved focus
- • No addiction potential (unlike benzodiazepines)
- • Stress resilience
- • Improved mood
- • Anti-inflammatory effects
Side effects
- • Very well tolerated
- • Rare: headache
- • Nasal irritation (with intranasal use)
Contraindications
- • Pregnancy
- • History of psychosis (caution)
- • Other GABA-active medications (interaction)
Gender notes
Men
Same dose. Popular among 'high performers' with anxiety.
Women
Same dose. Popular for hormonal anxiety, especially PMS-related.
Research
- Medvedev VE et al: Selank in generalized anxiety ↗
Russian clinical trial showing significant reduction in anxiety vs placebo.
Zhurnal Nevrologii i Psikhiatrii · 2014
- Inozemtseva LS et al: Selank molecular mechanisms ↗
Review of Selank's BDNF/GABA mechanisms.
Doklady Biological Sciences · 2008
Stacks well with
Track Selank doses in the app
Built-in reconstitution calculator, dose log, and reminders. Free on Android.
Get on Google PlayEducational use only. Not medical advice. Many peptides shown are not FDA-approved and remain research compounds. Always consult a qualified healthcare provider.