CJC-1295 (no DAC)

★ 90

Modified GRF 1-29

GHRH analog — amplifies the natural GH pulse

Muscle Growth

Half-life

30 min - 2 hours (no DAC), 6-8 days (with DAC)

Route

SubQ

Cycle

12-16 weeks on,

Status

Phase II trials

About

A synthetic GHRH (Growth Hormone Releasing Hormone) analog that activates pituitary GHRH receptors. Without DAC, the short half-life preserves natural pulsatility.

Mechanism

Binds GHRH receptors in pituitary somatotrophs, stimulating GH production and release.

Dosage

beginner

Amount: 100 mcg
Frequency: 1x per day before sleep
Route: SubQ
Duration: 8-12 weeks

standard

Amount: 100-200 mcg
Frequency: 1-2x per day
Route: SubQ
Duration: 12-16 weeks

advanced

Amount: 200-300 mcg
Frequency: 2-3x per day (synced with meals)
Route: SubQ
Duration: 16 weeks with a 4-week break

Timing

Best on an empty stomach, 30-60 min before food or sleep. Almost always paired with Ipamorelin.

Cycle structure

12-16 weeks on, 4 weeks off

Reconstitution & Storage

5 mg + 2 mL → 2500 mcg/mL

Can be combined with Ipamorelin in the same syringe (same concentration).

Lyophilized: freezer. Reconstituted: 2-8°C, 28 days.

Benefits

• Raises GH and IGF-1
• Muscle building
• Fat loss (especially visceral)
• Improved sleep
• Slower aging
• Improved energy and recovery

Side effects

• Facial flushing — transient
• Tingling
• Headache
• Fluid retention (rare)

Contraindications

• Active cancer
• Pregnancy
• Pituitary disease
• Insulin resistance (caution)

Gender notes

Men

Common stack: 200 mcg + 200 mcg Ipamorelin nightly.

Women

Start at 100 mcg + 100 mcg Ipamorelin. Sensitivity is higher.

Research

Teichman SL et al: CJC-1295 sustained GH release ↗
Trial of CJC-1295 with and without DAC, showing sustained GH and IGF-1 elevation.

Journal of Clinical Endocrinology & Metabolism · 2006
Ionescu M, Frohman LA: CJC-1295 in healthy adults ↗
Clinical trial of CJC-1295 in healthy adults.

Journal of Clinical Endocrinology & Metabolism · 2006

Stacks well with

IPAMORELIN BPC-157 TESAMORELIN

Track CJC-1295 (no DAC) doses in the app

Built-in reconstitution calculator, dose log, and reminders. Free on Android.

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Educational use only. Not medical advice. Many peptides shown are not FDA-approved and remain research compounds. Always consult a qualified healthcare provider.