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Melanotan II

★ 65

Melanotan II (MT-II)

Bronze tan + libido

Sexual Health
Half-life
~1 hour
Route
SubQ
Cycle
Loading 4-8 weeks,
Status
Not approved — research compound

About

A cyclic melanocortin receptor agonist — developed as a tanning peptide. Also has libido effects.

Mechanism

Activates MC1R (melanin, tanning) and MC3R/MC4R (libido, appetite).

Dosage

beginner

Amount
250 mcg
Frequency
1x per day (loading)
Route
SubQ
Duration
4-8 weeks loading

standard

Amount
500 mcg
Frequency
1x per day (loading), then 2-3x/week maintenance
Route
SubQ
Duration
Loading 4-8 weeks, then maintenance

advanced

Amount
1000 mcg
Frequency
1x per day loading, then 2-3x/week
Route
SubQ
Duration
Continuous with breaks
Timing

In the evening (usually). UV exposure (sun/tanning bed) is needed for 1-2 days after dosing to activate the tan.

Cycle structure

Loading 4-8 weeks, then low-dose maintenance.

Reconstitution & Storage

10 mg + 1 mL → 10000 mcg/mL

10 units on an insulin syringe = 333 mcg.

Dosing reference — units to draw

Concentration = peptide mass ÷ bacteriostatic water; units to draw = dose volume (mL) × 100 on a U-100 insulin syringe. Each vial size below is shown at 1 mL, with the units to draw for a typical 500–1000 mcg dose.

Melanotan II reconstitution: vial size, bacteriostatic water, resulting concentration, and units to draw on a U-100 insulin syringe for a typical dose.
Vial BAC water Concentration Units to draw
10 mg 1 mL 10000 mcg/mL 5–10 units

Open Melanotan II in the reconstitution calculator →

Lyophilized: freezer. Reconstituted: 2-8°C, 4-6 weeks.

Benefits

  • • Dark and long-lasting tan
  • • Sunburn protection (theoretical)
  • • Increased libido
  • • Reduced appetite (bonus)

Side effects

  • • Nausea (common at first)
  • • Flushing
  • • Darkening of freckles and moles
  • • Spontaneous erections (men)
  • • IMPORTANT: monitor any new or changed moles

Contraindications

  • • History of melanoma
  • • Many moles on the skin
  • • Familial dysplastic nevus syndrome
  • • Pregnancy
  • • Cardiovascular disease

Gender notes

Men

Sometimes causes unexpected erections initially. Lower doses are often sufficient.

Women

Popular for tanning. Caution with moles — see a dermatologist regularly.

Research

Stacks well with

PT-141

Melanotan II FAQ

How do you reconstitute Melanotan II?

Add 1 mL of bacteriostatic water to a 10 mg vial of Melanotan II, which gives a concentration of 10000 mcg/mL. Inject the water slowly down the vial wall and swirl gently — never shake.

What is a typical Melanotan II dose?

A typical research dose of Melanotan II is 500–1000 mcg, 1x per day (loading), then 2-3x/week maintenance. This is educational information, not medical advice.

How many units of Melanotan II do I draw?

From a 10 mg vial reconstituted with 1 mL of bacteriostatic water, draw 5–10 units on a U-100 insulin syringe for a 500–1000 mcg dose.

Track Melanotan II doses in the app

Built-in reconstitution calculator, dose log, and reminders. Free on Android.

Get on Google Play

Educational use only. Not medical advice. Many peptides shown are not FDA-approved and remain research compounds. Always consult a qualified healthcare provider.