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TB-500

★ 85

Thymosin Beta-4 (fragment)

Systemic tissue repair

Healing & Recovery
Half-life
~2-3 days
Route
SubQ or IM
Cycle
4-8 weeks on,
Status
Strong preclinical

About

A synthetic fragment of Thymosin Beta-4. Promotes cell migration, angiogenesis and regeneration of muscle, skin and connective tissue.

Mechanism

Binds G-actin to promote cell motility and repair of damaged tissue.

Dosage

beginner

Amount
2 mg
Frequency
1-2x per week
Route
SubQ or IM
Duration
4-6 weeks

standard

Amount
2-2.5 mg
Frequency
2x per week (loading 4-6 weeks), then 2 mg/week maintenance
Route
SubQ or IM
Duration
6-12 weeks

advanced

Amount
5 mg loading
Frequency
2x per week for 4 weeks, then 2 mg/week
Route
SubQ or IM
Duration
12 weeks
Timing

Timing matters little due to the long half-life. Commonly taken in the evening.

Cycle structure

4-8 weeks on, 2-4 weeks off

Reconstitution & Storage

5 mg + 1 mL → 5 mg/mL

Low mg per dose, so 2.5 mL yields convenient unit measurements.

Dosing reference — units to draw

Concentration = peptide mass ÷ bacteriostatic water; units to draw = dose volume (mL) × 100 on a U-100 insulin syringe. Each vial size below is shown at 1 mL, with the units to draw for a typical 2.5–5 mg dose.

TB-500 reconstitution: vial size, bacteriostatic water, resulting concentration, and units to draw on a U-100 insulin syringe for a typical dose.
Vial BAC water Concentration Units to draw
5 mg 1 mL 5 mg/mL 50–100 units
10 mg 1 mL 10 mg/mL 25–50 units
20 mg 1 mL 20 mg/mL 12.5–25 units

Open TB-500 in the reconstitution calculator →

Lyophilized: freezer or fridge. Reconstituted: 2-8°C, 4 weeks.

Benefits

  • • Systemic tissue repair
  • • Improves mobility
  • • Helps with deep injuries
  • • Vascular regeneration
  • • Supports hair growth

Side effects

  • • Generally very well tolerated
  • • Rare: fatigue at start
  • • Headache (very rare)

Contraindications

  • • Pregnancy
  • • Active cancer
  • • Autoimmune disease (caution)

Gender notes

Men

Popular after sports injuries. Same dosing.

Women

Same dosing. Helps with hair growth and skin health.

Research

Stacks well with

BPC-157 GHK-CU IPAMORELIN

TB-500 FAQ

How do you reconstitute TB-500?

Add 1 mL of bacteriostatic water to a 5 mg vial of TB-500, which gives a concentration of 5 mg/mL. Inject the water slowly down the vial wall and swirl gently — never shake.

What is a typical TB-500 dose?

A typical research dose of TB-500 is 2.5–5 mg, 2x per week (loading 4-6 weeks), then 2 mg/week maintenance. This is educational information, not medical advice.

How many units of TB-500 do I draw?

From a 5 mg vial reconstituted with 1 mL of bacteriostatic water, draw 50–100 units on a U-100 insulin syringe for a 2.5–5 mg dose.

Track TB-500 doses in the app

Built-in reconstitution calculator, dose log, and reminders. Free on Android.

Get on Google Play

Educational use only. Not medical advice. Many peptides shown are not FDA-approved and remain research compounds. Always consult a qualified healthcare provider.