Thymosin α-1
★ 82 FDA approvedThymosin Alpha-1 (Zadaxin)
Immune modulator and T-cell support
Healing & RecoveryAbout
A 28-amino-acid peptide that regulates T-cell maturation. FDA approved in 35+ countries (as Zadaxin) for hepatitis B and as an adjuvant in cancer therapy. Key in immune response.
Mechanism
Boosts Th1 response, activates dendritic cells and NK cells, balances cytokine production.
Dosage
beginner
- Amount
- 1.6 mg
- Frequency
- 2x per week
- Route
- Subcutaneous (SubQ)
- Duration
- 4-12 weeks
standard
- Amount
- 1.6 mg
- Frequency
- 1x per day (5 days per week)
- Route
- Subcutaneous (SubQ)
- Duration
- 6-8 weeks
advanced
- Amount
- 3.2 mg
- Frequency
- 2x per week
- Route
- Subcutaneous (SubQ)
- Duration
- 8-12 weeks
Timing matters little — morning or evening is fine.
Standard course is 4-12 weeks with a break before any repeat course.
Reconstitution & Storage
Very stable peptide. Tolerates freezing after reconstitution (unlike many others).
Lyophilized: refrigerated, 24+ months. After reconstitution: 2-8°C for 30 days or -20°C for 6 months.
Benefits
- • Strengthens the immune system (especially T cells)
- • Helps with chronic viral infections
- • Adjuvant in cancer therapy
- • Very safe for long-term use
- • Improves wound healing via immune mediation
Side effects
- • Very well tolerated
- • Rare: injection-site irritation
- • Rare: mild fatigue in the first weeks
Contraindications
- • Autoimmune disease (caution — may increase immune activity)
- • Organ transplantation (immunosuppression required)
- • Pregnancy (limited data)
Gender notes
Men
Same dose as general protocol.
Women
Same dose. Well-studied in women with HBV.
Research
- Camerini & Garaci: Historical review of Thymosin α1 ↗
Review of 40 years of use: immune support, cancer, infections.
Annals of the New York Academy of Sciences · 2015
- Liu et al: Thymosin alpha-1 in chronic HBV ↗
Meta-analysis of 23 trials, effective for HBV clearance.
Hepatology International · 2020
Stacks well with
Track Thymosin α-1 doses in the app
Built-in reconstitution calculator, dose log, and reminders. Free on Android.
Get on Google PlayEducational use only. Not medical advice. Many peptides shown are not FDA-approved and remain research compounds. Always consult a qualified healthcare provider.