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Thymosin α-1

★ 82 FDA approved

Thymosin Alpha-1 (Zadaxin)

Immune modulator and T-cell support

Healing & Recovery
Half-life
~2 hours (SubQ)
Route
Subcutaneous (SubQ)
Cycle
Standard course is
Status
Approved in many countries

About

A 28-amino-acid peptide that regulates T-cell maturation. FDA approved in 35+ countries (as Zadaxin) for hepatitis B and as an adjuvant in cancer therapy. Key in immune response.

Mechanism

Boosts Th1 response, activates dendritic cells and NK cells, balances cytokine production.

Dosage

beginner

Amount
1.6 mg
Frequency
2x per week
Route
Subcutaneous (SubQ)
Duration
4-12 weeks

standard

Amount
1.6 mg
Frequency
1x per day (5 days per week)
Route
Subcutaneous (SubQ)
Duration
6-8 weeks

advanced

Amount
3.2 mg
Frequency
2x per week
Route
Subcutaneous (SubQ)
Duration
8-12 weeks
Timing

Timing matters little — morning or evening is fine.

Cycle structure

Standard course is 4-12 weeks with a break before any repeat course.

Reconstitution & Storage

10 mg + 1 mL → 10 mg/mL

Very stable peptide. Tolerates freezing after reconstitution (unlike many others).

Dosing reference — units to draw

Concentration = peptide mass ÷ bacteriostatic water; units to draw = dose volume (mL) × 100 on a U-100 insulin syringe. Each vial size below is shown at 1 mL, with the units to draw for a typical 3–8 mg dose.

Thymosin α-1 reconstitution: vial size, bacteriostatic water, resulting concentration, and units to draw on a U-100 insulin syringe for a typical dose.
Vial BAC water Concentration Units to draw
10 mg 1 mL 10 mg/mL 30–80 units

Open Thymosin α-1 in the reconstitution calculator →

Lyophilized: refrigerated, 24+ months. After reconstitution: 2-8°C for 30 days or -20°C for 6 months.

Benefits

  • • Strengthens the immune system (especially T cells)
  • • Helps with chronic viral infections
  • • Adjuvant in cancer therapy
  • • Very safe for long-term use
  • • Improves wound healing via immune mediation

Side effects

  • • Very well tolerated
  • • Rare: injection-site irritation
  • • Rare: mild fatigue in the first weeks

Contraindications

  • • Autoimmune disease (caution — may increase immune activity)
  • • Organ transplantation (immunosuppression required)
  • • Pregnancy (limited data)

Gender notes

Men

Same dose as general protocol.

Women

Same dose. Well-studied in women with HBV.

Research

Stacks well with

BPC-157 TB-500 LL-37

Thymosin α-1 FAQ

How do you reconstitute Thymosin α-1?

Add 1 mL of bacteriostatic water to a 10 mg vial of Thymosin α-1, which gives a concentration of 10 mg/mL. Inject the water slowly down the vial wall and swirl gently — never shake.

What is a typical Thymosin α-1 dose?

A typical research dose of Thymosin α-1 is 3–8 mg, 1x per day (5 days per week). This is educational information, not medical advice.

How many units of Thymosin α-1 do I draw?

From a 10 mg vial reconstituted with 1 mL of bacteriostatic water, draw 30–80 units on a U-100 insulin syringe for a 3–8 mg dose.

Track Thymosin α-1 doses in the app

Built-in reconstitution calculator, dose log, and reminders. Free on Android.

Get on Google Play

Educational use only. Not medical advice. Many peptides shown are not FDA-approved and remain research compounds. Always consult a qualified healthcare provider.